Valproic Acid, Divalproex Sodium delayed-release tablets or sprinkle capsules
What do divalproex sodium delayed-release tablets or capsules do?
DIVALPROEX SODIUM (Depakote(R)) can help with seizure (convulsion) control in certain types of epilepsy. This drug also is used for other conditions, such as treatment of bipolar disorder, mania, migraines, and behavioral problems associated with Alzheimer’s disease or dementia.
What should my health care professional know before I take divalproex sodium?
They need to know if you have any of these conditions:
brain damage or disease
low blood proteins
an unusual or allergic reaction to divalproex sodium, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
How should I take this medicine?
Take divalproex sodium tablets or capsules by mouth. Follow the directions on the prescription label. Swallow the tablets whole with a drink of water; do not crush or chew. The capsules can be swallowed whole or opened carefully and the contents sprinkled on about one teaspoonful of applesauce or pudding. This mixture must be swallowed immediately; do not chew or store for later use. If divalproex sodium upsets your stomach, take it with food or milk; do not take with carbonated drinks. Take your doses at regular intervals. Do not take your medicine more often than directed.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?
If you take only one dose each day, take the missed dose as soon as you remember. If you do not remember until the next day, skip the missed dose and go on with your regular schedule. Do not take double or extra doses. If you take more than one dose a day and miss a dose, take it if you remember within 6 hours. Space the other doses for that day at regular intervals, do not take two doses at once.
What other medicines can interact with divalproex sodium?
agents that dissolve blood clots
antiinflammatory drugs (NSAIDs, such as ibuprofen)
barbiturate medicines for inducing sleep or treating seizures (convulsions)
medicines for mental depression
medicines for mental problems and psychotic disturbances
other seizure (convulsion) or epilepsy medicines
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What side effects may I notice from taking divalproex sodium?
agitation, restlessness, irritability, or other changes in mood
Side effects that you should report to your prescriber or health care professional as soon as possible:
blurred or double vision or uncontrollable eye movements
changes in the frequency or severity of seizures
double vision, or involuntary eye movements
redness, blistering, peeling or loosening of the skin, including inside the mouth
skin rash or itching
stomach pain or cramps
trembling of hands or arms
unusual bleeding or bruising or pinpoint red spots on the skin
unusual swelling of the arms or legs
unusual tiredness or weakness
yellowing of skin or eyes
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
breast enlargement, unusual production of breast milk
changes in menstrual periods
clumsiness or unsteadiness
diarrhea or constipation
dizziness or drowsiness
increased sensitivity to sun or ultraviolet light
irregular menstrual cycle
loss of bladder control
loss of hair or unusual growth of hair
loss or increase in appetite
nausea or vomiting
skin rash, itching
weight gain or loss